Use of isotretinoin among girls and women of childbearing age and occurrence of isotretinoin-exposed pregnancies in Germany: A population-based study.

BackgroundExposure to isotretinoin during pregnancy must be avoided due to its teratogenicity, but real-world data on its use are scarce.We aimed to describe (i) isotretinoin use in women of childbearing age in Germany; (ii) the occurrence of isotretinoin-exposed pregnancies; and (iii) malformations among children exposed in utero.Methods and findi

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Iron compounds for food fortification: The development of an essential nutritional strategy for developing countries. A review

Iron (Fe) deficiency has been recognized as a public health problem due to its health and economic implications.In developing countries like Colombia this deficiency still affects a large part of its population, especially children and women in gestation.Hence the importance of developing strategies such as food fortification with iron to improve t

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Human Archaeological Dentin as Source of Polar and Less Polar Metabolites for Untargeted Metabolomic Research: The Case of Yersinia pestis

Metabolomic approaches, such as ACETYL-L-CARNITINE in clinical applications of living individuals, have shown potential use for solving questions regarding the past when applied to archaeological material.Here, we study for the first time the potential of this Omic approach as applied to metabolites extracted from archaeological human dentin.Dentin

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Functional outcomes of bowel resection versus shaving or disc excision of colorectal endometriosis: a systematic review protocol

Introduction Endometriosis is a prevalent gynaecological condition for women of reproductive age worldwide.While endometriosis primarily involves the reproductive system, it can also infiltrate additional viscera such as the gastrointestinal tract.Patients with colorectal endometriosis can have severe symptoms that require surgical intervention.The

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